Neuropathology
Neuropathology Scheme
The Neuropathology Scheme assesses 2 archival surgical Haematoxylin and Eosin (H&E) stained sections, and 2 special stained sections.This scheme has been running since 2001 and is available to both public and private institutions within the UK and overseas.
Staining Criteria Handbook available in Members' Area
No. of assessment runs:
6 distributions over a 12 month period
Stains assessed:
Selected / In-house Material
Haematoxylin and Eosin (H&E) (all runs)
Distributed Material
Special A
Diastase / PAS
Elastin / van Gieson
Gram
Perls’ Prussian blue
Reticulin (silver method for)
Ziehl-Neelsen
Distributed Material
Special B
Axonal Swelling (method for)
Glial fibres (method for)
Myelin (method for)
Neurofibrillary tangles
Nissl substance
Senile plaques (method for)
Stain A comprises routine histology special stains, and stain B comprises specialist neuropathological methods. Two pairs of unstained sections are provided to each participant for staining by the special stain methods (designated on the accompanying delivery letter issued with each run) with one of each to be submitted for assessment.
If a method is not specified, the laboratory / organisation are free to use any suitable technique to demonstrate the target. For neuropathology, the methods in list B may include immunocytochemical techniques where that is the organisation’s method of choice.
