Neuropathology Scheme

Neuropathology  Scheme

The Neuropathology Scheme assesses 2 archival surgical Haematoxylin and Eosin (H&E) stained sections, and 2 special stained sections.This scheme has been running since 2001 and is available to both public and private institutions within the UK and overseas. 

 

Staining Criteria Handbook available in Members' Area
No. of assessment runs: 
6 distributions over a 12 month period 

Stains assessed:
Selected / In-house Material
Haematoxylin and Eosin (H&E) (all runs) 

Distributed Material
Special A
Diastase / PAS 
Elastin / van Gieson 
Gram 
Perls’ Prussian blue 
Reticulin (silver method for) 
Ziehl-Neelsen 

Selected / In House Material

Special B

Axonal Swelling (method for)

Glial fibres (method for)

Myelin (method for)

Neurofibrillary tangles

Nissl substance

Senile plaques (method for)



Stain A comprises routine histology special stain, and stain B comprises specialist neuropathological methods. Participants will be expected to submit 2 H&E stained sections plus, specialist stain B from their patient archives. 2 unstained sections will continue to be provided to each Participant for routine Cellular Pathology method stain A.


For Special B, where a method is not specified, the laboratory / organisation are free to use any suitable technique to demonstrate the target. For neuropathology, the methods in list B may include immunocytochemical techniques where that is the organisation’s method of choice.


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